Tetrapyrroles and derivatives
Abcam SB-3CT, MMP-2 and MMP-9 inhibitor, 5MG
MW 306.4 Da, Purity >98%. Potent, competitive and non-selective MMP-2 and MMP-9 inhibitor (Ki values are 13.9 and 600 nM for MMP-2 and MMP-9 respectively). Does not alter the activity of MMP-1, MMP-3 or MMP-7 (Ki values are 206 (MMP-1), 15 (MMP-3) and 96 (MMP-7) μM). Neuroprotective and blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam BIM 23052, Somatostatin (sst5) receptor 5 agonist, 1MG
MW 1122.33 g/mol. Selective somatostatin (sst₅) receptor 5 agonist (Ki values are 7.3 (sst₅), 13.5 (sst₂), 31.3 (sst₁) and 141 nM (sst₄)). Role in gastrointestinal and neuroendocrine systems. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Hemin BioXtra from Porcine5G
REAGENT Hemin BioXtra from Porcine5G
Sigma Aldrich Fine Chemicals Biosciences Methylcobalamin vitamin B125MG
Methylcobalamin (MeCbl) is an analog of vitamin B12 (cobalamin). It differs from cobalamin by containing a methyl group. The physiologically active form of vitamin B12 include methylcobalamin and adenosylcobalamin.
Cayman Chemical MethylcobalamIn 1g
An endogenous peptide with cardiovascular functions an agonist of NPR1/GC-A and NPR3 (Kd 7 3 and 13 pM respectively for human chimeric extracellular receptors) binds human recombinant NPR1/GC-A and NPR3 (IC50s 8 and 2 6 nM respectively) activates NPR1/GC-A and increases cGMP levels in HEK293 cells (EC50 27 nM) stimulates cGMP accumulation in bovine aortic endothelial and aortic smooth muscle cells (EC50s 9 and 17 nM respectively) relaxes PGF2a-induced contractions in isolated porcine coronary artery and rat aortic strips (IC50s 0 02 and 12 1 nM respectively) increases mean urine flow and the sodium excretion rate in rats (10 nmol/kg)
Sigma Organic Chemistry Dilithium phthalocyanine | 1G | 25510-41-2 | MFCD00059094
Dilithium phthalocyanine, 1G
About This Item:
Storage: room temp
Sigma Organic Chemistry Magnesium phthalocyanine | 1G | 1661-03-6 | MFCD00041953
Magnesium phthalocyanine, 1G
About This Item:
Storage: room temp
EINECS Number: 216-766-6
Sigma Organic Chemistry Zinc phthalocyanine | 25G | 14320-04-8 | MFCD00041955
Zinc phthalocyanine, 25G
About This Item:
Storage: room temp
EINECS Number: 238-262-5
Selleck Chemical LLC Tin protoporphyrin IX
Tin Protoporphyrin IX dichloride is a potent inhibitor of heme oxygenase-1 (HO-1) reduces ozone-induced pulmonary inflammation and BAL cell necrosis highlighting its protective role It also sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in a mouse model suggesting its potential for PDAC treatment
Frontier Specialty Chemicals 5g meso-Tetra(pentafluorophenyl)porphine chlorin free, 25440-14-6 MFCD00010032
meso-Tetra(pentafluorophenyl)porphine chlorin free5,10,15,20-Tetrakis(pentafluorophenyl)-21H,23H-porphine CAS: 25440-14-6 MFCD00010032 Porphyrins Synthetic Porphyrins
Apexbio Technology LLC Vitamin B12 68-19-9 10mM (in 1mL DMSO)
Vitamin B12 (CAS 68-19-9) is a cobalt-containing water-soluble vitamin involved in hematopoiesis and neuronal function It acts primarily as a cofactor facilitating methyl-transfer reactions notably as methylcobalamin in the synthesis pathway of methionine consequently regulating methylation of DNA RNA and proteins Additionally Vitamin B12 modulates cellular redox homeostasis offering protective effects against oxidative cellular damage Current research engages Vitamin B12 in studies on neurodegenerative disease models immunological inflammation pathways and cellular injury mechanisms related to oxidative stress
Apexbio Technology LLC CHLORIN E6 250MG
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Apexbio Technology LLC TIN PROTOPORPHYRIN IX 2CL 10MG
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways
Apexbio Technology LLC TIN PROTOPORPHYRIN IX 2CL 25MG
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways